PC 602 – Pharmaceutical Nanotechnology

Course lecturer :

Dr. Noha Soliman El-Salamouni
Dr. Wessam Magdy Refaie

Course assistant :

Course objectives :

The main objectives of this course are based upon the acquisition of knowledge and developing research abilities in the field of Pharmaceutical Nanotechnology, respective to the: • Development of therapeutic nano-systems for the release and vectorisation of drugs with chemical and biotechnological origin. • Chemical preparation & analysis of nanomaterial and the chemical study of nanostructures. This course has been developed to introduce students to the underlying principles and applications of the emerging field of nanotechnology, scientific principles and theory relevant at the nanoscale dimension and to discuss the current and future nanotechnology applications in physics, chemistry, biology, pharmacy and medicine.

Course description :

• Introduction to the practice and discipline of nanotechnology. • The fundamental science behind nanotechnology: • Overview of chemistry fundamentals for Nanotechnology. • Overview of physics fundamentals for Nanotechnology. • Biosystems and Molecular recognition. • Nanostructures & Nanomaterials. • Nanofabrication & tools for measuring nanostructures. • Materials characterization methods. • Structural study of organic/inorganic nanocomposites. • Surface, thin film and colloid chemistry. • Nanobiotechnology. • Pharmaceutical nanotechnology: • Drug delivery systems, emulsions, microemulsions and multiple emulsions. • Micro-nano capsules and micro-nano spheres, liposomes and niosomes.

Course assessment :

This course is 2 Credits (200 marks) as follows: • Final written exam 40% (80 marks) • Final oral exam 10% (20 marks) • Mid-term written exam 20% (40 marks) • Course work 30% (60 marks)

Recommended text books :

• M.M. De Villiers, P. Aramwit, G.S. Kwon, Nanotechnology in drug delivery, Springer Science & Business Media, 2008.

Recommended refrences :

• J. Shi, A.R. Votruba, O.C. Farokhzad, R. Langer, Nanotechnology in drug delivery and tissue engineering: from discovery to applications, Nano letters. 10 (2010) 3223-3230. • B.V. Bonifácio, P.B. da Silva, M.A. dos Santos Ramos, K.M.S. Negri, T.M. Bauab, M. Chorilli, Nanotechnology-based drug delivery systems and herbal medicines: a review.