MLEC-301 – Etiology of cancer

Course lecturer :

Dr Hewaida Fadel

Course assistant :

Omnia Aly

Course objectives :

The etiology of cancer course focuses on the risk factors causing different types of cancer, in addition to, studying the mechanism of initiation, promotion and progression of cancer. a1. Identify types of articles and their compositions. a2-List the risk factors of cancer. a3- Identify the aim of scientific research in cancer chemistry. a3- Demonstrate the mechanism of induction of cancer a5- Recognize the mechanism of carcinogenesis. a6-List some carcinogenic agents. a7-Identify the metabolism of xenobiotics a8-Recognize the relationship between xenobiotics and cancer. a9-Identify the molecular basics of cancer. a10-Recognize the role of mutation in induction of cancer. a11- List some oncogenes and tumor suppressor genes. a12-Recognize the relationship between free radicals and mutation resulting in carcinogenesis.

Course description :

-Carcinogenesis -Epidemiology and risk factors -Metabolism of xenobiotics -Free Radicals -Molecular biology of cancer

Course assessment :

75 final theoretical exam 15 midterm exam 10 assignment

Recommended text books :

David J. Kerr, Daniel G. Haller, Cornelis J. H. van de velde, Michael Bauman. Oxford textbook of Oncology, 2nd edition, 2012.

Recommended refrences :

The Biology of Cancer. Robert A. Weinberg. 2nd edition.2010