I. Department of Pharmaceutical Chemistry (PC)

The Department aims to provide pharmacy students with the foundation and basic understanding of different branches of chemistry namely pharmaceutical analytical chemistry, pharmaceutical organic chemistry and medicinal chemistry.

The department gives students the conceptual and intellectual foundation for further studies in pharmaceutical research skills, working in teams, solving problems and preparation of reports.

Courses Offered or Supervised by Department of Pharmaceutical Chemistry (PC) : Pharm D – (New Bylaw 2019)

Required Courses
Course Title Pharmaceutical Analytical Chemistry I
Course Code PCD 101 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course is designed to provide the students with the fundamentals of thermochemistry and thermodynamics. Chemical kinetics and reaction rates. Chemical equilibrium. Introduction to qualitative inorganic chemistry. Quantitative volumetric analysis. Volumetric calculation and concentration expressions. It also covers acid-base titrations.
Course Title Pharmaceutical Organic Chemistry I
Course Code PCD 102 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course includes an introduction to nomenclature, synthesis and reactions of: alkanes, alkenes, alkynes, alkyl halides, alcohols and ethers. Stereochemistry (Structural, geometrical and optical isomerism).
Course Title Mathematics
Course Code PCD 103 Credit Hours 1 Lecture 1 Tutorial 1 Practical 0
Course Description:
This course provides the students with some essential elements of mathematics such as: Functions, limits, derivatives of 1st and higher orders, integration, exponents, logarithm, probability and random variables, significant figures, in addition to pharmaceutical calculation.
Course Title Information Technology I
Course Code PCD 104 Credit Hours 2 Lecture 1 Tutorial 0 Practical 2
Course Description:
This course is designed to provide students with a brief introduction to the world of computers and the concept of information technology including: number systems and data representation, computer system components: hardware & software, storage and input/output systems, operating systems and utility Systems, software applications. In addition, it gives an overview about computer networks and internet: data communication, transmission modes, transmission media, computer networks, internet protocol, and internet services. It gives some computer applications in the laboratory such as internet access, word processing and power point. It is also concerned with Pharmacy Informatics and the use of technology to improve patient care as well as increasing patient safety by  dealing with data generated by software used in patient care, not only the storage of data but also the retrieval of data as meaningful clinical reports and the management of information systems to assure patient safety and optimal medical outcomes.
Course Title Pharmaceutical Analytical Chemistry II
Course Code PCD 105 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course deals with precipitation titration (Mohr, Fajan and Volhard methods), complex formation titration (Types of ligands, coordination number, argentometric and mercurimetric titration, EDTA titrations), introduction to oxidation- reduction titrations (Balancing redox reactions and principles of Nernst equation and cell potential) and applications of oxidation-reduction titrations: selected oxidants and reductants.
Course Title Pharmaceutical Organic Chemistry II
Course Code PCD 106 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course deals with the chemistry of aromatic compounds. Electrophilic aromatic substitution reactions. The chemistry and reactions of ethers, epoxides, aldehydes, ketones, carboxylic acids and their derivatives: Acid halides, anhydrides, esters and acidamides.The chemistry and reactions of phenols, sulphonic acids and sulphonamides.
Course Title Pharmaceutical Analytical Chemistry III
Course Code PCD 201 Credit Hours 2 Lecture 1 Tutorial 1 Practical 2
Course Description:
This course introduces the students to electrochemistry and oxidation-reduction reactions. It covers the topics of electrode potential, Nernst equation and cell potential. Galvanic and electrolytic cells. Titration curves. Redox indicators. Selected oxidants and reductants. Application of oxidation – reduction titrations.
Course Title Pharmaceutical Organic Chemistry III
Course Code PCD 202 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course covers the chemistry of aromatic nitro compounds, amines: classification, nomenclature, basicity and synthesis of different classes of amines, reactions with different electrophiles, differentiation between the three classes. It gives an overview of the structure, chemistry and stability of diazonium salts at different pH values. Overview on nomenclature, synthesis of some heterocyclic compounds including derivatives of pharmaceutical importance. Carbohydrates. Amino acids. Introduction to the use of different spectroscopic tools: UV, IR, NMR and MS.
Course Title Instrumental Analysis
Course Code PCD 203 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course provides the students with an overview of different instrumental methods of analysis with special emphasis on molecular ultraviolet-visible absorption spectroscopy (theory, instrumentation and application), molecular fluorescence spectroscopy (theory, instrumentation and application), atomic absorption and emission spectroscopy, polarimetry and refractometry. It also covers water and lipid analysis.
Course Title Electroanalytical Methods
Course Code PCD 204 Credit Hours 1 Lecture 1 Tutorial 1 Practical 0
Course Description:
This course provides the students with an overview of different electrochemical methods of analysis, with special emphasis on potentiometry, conductometry, polarography, derivatization polarography, electrogravimetry, coulometry and voltammetry.
Course Title Medicinal Chemistry I
Course Code PCD 301 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course deals with the chemistry, properties and mechanism of action of different classes of chemotherapeutic agents and diagnostic agents that treat different infections, including antivirals, antineoplastics, antibacterial sulfonamides, antimycobacterium, antifungal agents, local anti-infective agents, antibiotics, antiprotozoal agents, anthelmintics, antibilharzial agents and urinary tract anti- infectives.
Course Title Medicinal Chemistry II
Course Code PCD 302 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course includes important chemical, biochemical and pharmacological aspects of medicinal and pharmaceutical agents that belong to different categories. An overview of NSAIDs, opioids, CNS drugs, CV drugs, Steroids, GIT drugs, drugs acting on the respiratory system, drugs affecting neurotransmission as well as drugs acting on immune system and neuromuscular disorders.
Course Title Drug Design
Course Code PCD 401 Credit Hours 2 Lecture 1 Tutorial 1 Practical 2
Course Description:
This course introduces essentials of pharmaceutical chemistry and metabolism. Development of prodrugs, soft drugs, hard drugs. Computer aided drug design. Type of receptors, mode of interaction of drugs with receptors. In silico drug design. Quantitative structure activity relationship. Computer visualization and molecular modeling.
Course Title Information Technology II
Course Code PCD 402 Credit Hours 2 Lecture 1 Tutorial 0 Practical 2
Course Description:
The aim of this course is to teach newcomers spreadsheet, Databases and Hypertext markup language. The course aims to enable the student to carry out simple or more complicated calculations using numerical data and formulas using the variety of tasks that spreadsheets are used. The course also aims to help students to analyze, organize, and manipulate data. The course aims to help students, regardless of their major, to feel justifiably confident of their ability to create static webpage’s using HTML.
Course Title Analytical Quality Control of Pharmaceuticals
Course Code PCD 501 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course Description:
This course includes sampling of Pharmaceutical materials. Quality assurance and quality control. Validation of analytical procedures; accuracy, precision, specificity, linearity, range, detection limit and quantitation limit, ruggedness and robustness. Qualifications of instruments: HPLC, spectrophotometers and pH- meters. Drug stability. Routes of drug degradation; stress testing and forced degradation. Documentation.
Elective courses
Course Title Chromatography and Separation Techniques
Course Code PCD E01 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course Description:
This course provides the students with principles, instrumentation and applications of chromatographic and other separation techniques including: Thin Layer Chromatography, High Performance Liquid Chromatography, Gas Chromatography, Ultra Performance Liquid Chromatography, Capillary Electrophoresis.
Course Title Analysis of food and flavours.
Course Code PCD E02 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course Description:
This course deals with the classification of flavouring agents and chemesthetic compounds found in food, their chemistry and methods of analysis. It also deals with the choice and application of the common analytical methods to the analysis of the different types of food, with special emphasis on the analysis of milk, carbohydrates and proteins. It is designed to provide information about chemical composition, processing, quality control and detection of adulteration of food stuffs.
Course Title Forensic analysis
Course Code PCD E03 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course Description:
The objective of this course is to provide students with the required knowledge in forensic analysis labs and chemistry of drugs of abuse. In addition, it gives a general overview of the chemical principles, methods and analytical instruments involved in trace analysis of poisons, drugs of abuse and/or their metabolites, in addition to heavy metals in different biological specimens such as hair, skin and biological fluids.

 

 

Pharm-D (Clinical Pharmacy) – (New Bylaw 2019):

 

Required Courses
Course Title Pharmaceutical Analytical Chemistry I
Course Code PCC 101 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course description:
This course is designed to provide the students with the fundamentals of Thermochemistry and thermodynamics. Chemical kinetics and reaction rates. Chemical equilibrium. Introduction to qualitative inorganic chemistry. Quantitative volumetric analysis. volumetric calculation and concentration expressions. It also covers acid-base titration.
Course Title Pharmaceutical Organic Chemistry  I
Course Code PCC 102 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course description:
This course includes an introduction to nomenclature, synthesis and reactions of: alkanes, alkenes, alkynes, alkyl halides, alcohols and ethers. Stereochemistry (Structural, geometrical and optical isomerism).
Course Title Mathematics
Course Code PCC 103 Credit Hours 1 Lecture 1 Tutorial 1 Practical 0
Course description:
This course provides the students with some essential elements of mathematics such as: Functions, limits, derivatives of 1st and higher orders, integration, exponents, logarithm, probability and random variables, significant figures, in addition to pharmaceutical calculation.
Course Title Information Technology I
Course Code PCC 104 Credit Hours 2 Lecture 1 Tutorial 0 Practical 2
Course description:
This course is designed to provide students with a brief introduction to the world of computers and the concept of information technology including: number systems and data representation, computer system components: hardware & software, storage and input/output systems, operating systems and utility Systems, software applications. In addition, it gives an overview about computer networks and internet: data communication, transmission modes, transmission media, computer networks, internet protocol, and internet services. It gives some computer applications in the laboratory such as internet access, word processing and power point. It is also concerned with Pharmacy Informatics and the use of technology to improve patient care as well as increasing patient safety by  dealing with data generated by software used in patient care, not only the storage of data but also the retrieval of data as meaningful clinical reports and the management of information systems to assure patient safety and optimal medical outcomes.
Course Title Pharmaceutical Analytical Chemistry II
Course Code PCC 105 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course description:
This course deals with precipitation titration (Mohr, Fajan and Volhard methods), complex formation titration (Types of ligands, coordination number, argentometric and mercurimetric titration, EDTA titrations), introduction to oxidation- reduction titrations (Balancing redox reactions and principles of Nernst equation and cell potential) and applications of oxidation-reduction titrations: selected oxidants and reductants.
Course Title Pharmaceutical Organic Chemistry II
Course Code PCC 106 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course description:
This course deals with the chemistry of aromatic compounds. Electrophilic aromatic substitution reactions. The chemistry and reactions of ethers, epoxides, aldehydes, ketones, carboxylic acids and their derivatives: Acid halides, anhydrides, esters and acidamides.The chemistry and reactions of phenols, sulphonic acids and sulphonamides.
Course Title Pharmaceutical Organic Chemistry  III
Course Code PCC 201 Credit Hours 2 Lecture 1 Tutorial 1 Practical 2
Course description:
This course covers the chemistry of aromatic nitro compounds, amines: classification, nomenclature, basicity and synthesis of different classes of amines, reactions with different electrophiles, differentiation between the three classes. It gives an overview of the structure, chemistry and stability of diazonium salts at different pH values. Overview on nomenclature, synthesis of some heterocyclic compounds including derivatives of pharmaceutical importance.
Course Title Instrumental Analysis
Course Code PCC 202 Credit Hours 2 Lecture 2 Tutorial 1 Practical 0
Course description:
This course provides the students with an overview of different instrumental methods of analysis with special emphasis on conductometry, molecular ultraviolet-visible absorption spectroscopy (theory, instrumentation and application), molecular fluorescence spectroscopy (theory, instrumentation and application), atomic absorption and emission spectroscopy, polarimetry and refractometry.
Course Title Medicinal Chemistry I
Course Code PCC 401 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course description
This course deals with the chemistry, properties and mechanism of action of different classes of chemotherapeutic agents and diagnostic agents that treat different infections, including antivirals, antineoplastics, antibacterial sulfonamides, antimycobacterium, antifungal agents, local anti-infective agents, antibiotics, antiprotozoal agents, anthelmintics, antibilharzial agents and urinary tract anti- infectives.
Course Title Analytical Quality Control of Pharmaceuticals
Course Code PCC 402 Credit Hours 2 Lecture 1 Tutorial 1 Practical 2
Course description:
This course includes sampling of Pharmaceutical materials. Quality assurance and quality control. Validation of analytical procedures; accuracy, precision, specificity, linearity, range, detection limit and quantitation limit, ruggedness and robustness. Qualifications of instruments: HPLC, spectrophotometers and pH- meters. Drug stability. Routes of drug degradation; stress testing and forced degradation.
Course Title Medicinal Chemistry II
Course Code PCC 403 Credit Hours 3 Lecture 2 Tutorial 1 Practical 2
Course description:
This course includes important chemical, biochemical and pharmacological aspects of medicinal and pharmaceutical agents that belong to different categories. An overview of NSAIDs, opioids, CNS drugs, CV drugs, Steroids, GIT drugs, drugs acting on the respiratory system, drugs affecting neurotransmission as well as drugs acting on immune system and neuromuscular disorders.
Course Title Information Technology II
Course Code PCC 404 Credit Hours 2 Lecture 1 Tutorial 0 Practical 2
Course description:
The aim of this course is to teach THE students spreadsheet, Databases and Hypertext markup language. The course aims to enable the student to carry out simple or more complicated calculations using numerical data and formulas using the variety of tasks that spreadsheets are used. The course also aims to help students to analyze, organize, and manipulate data. The course aims to help students, regardless of their major, to feel justifiably confident of their ability to create static webpage’s using HTML.
Elective Courses
Course Title Chromatography and Separation Techniques
Course Code PCC E01 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course description:
This course provides the students with principles, instrumentation and applications of chromatographic and other separation techniques including: Thin Layer Chromatography, High Performance Liquid Chromatography, Gas Chromatography, Ultra Performance Liquid Chromatography, Capillary Electrophoresis.
Course Title Drug Design
Course Code PCC E02 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course description:
This course introduces essentials of pharmaceutical chemistry and metabolism. Development of prodrugs, soft drugs, hard drugs. Computer aided drug design. Type of receptors, mode of interaction of drugs with receptors. In silico drug design. Quantitative structure activity relationship. Computer visualization and molecular modeling.
Course Title Analysis of food and flavours.
Course Code PCC E03 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course description:
This course deals with the classification of flavouring agents and chemesthetic compounds found in food, their chemistry and methods of analysis. It also deals with the choice and application of the common analytical methods to the analysis of the different types of food, with special emphasis on the analysis of milk, carbohydrates and proteins. It is designed to provide information about chemical composition, processing, quality control and detection of adulteration of food stuffs.
Course Title Forensic analysis
Course Code PCC E04 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course description:
The objective of this course is to provide students with the required knowledge in forensic analysis labs and chemistry of drugs of abuse. In addition, it gives a general overview of the chemical principles, methods and analytical instruments involved in trace analysis of poisons, drugs of abuse and/or their metabolites, in addition to heavy metals in different biological specimens such as hair, skin and biological fluids.
Course Title Overview Of spectroscopy
Course Code PCC E05 Credit Hours 2 Lecture 1 Tutorial 2 Practical 0
Course description:
This course is designed to provide the students basic knowledge about the use of different spectroscopic tools, including ultraviolet (UV), infrared (IR), nuclear magnetic resonance (NMR) and mass spectrometry (MS) both qualitatively (for the structural elucidation of organic compounds such as the degradation products of drugs during stability testing) and quantitatively (for drug analysis).